Trailhead specializes in precisely differentiating induced pluripotent stem cells (iPSCs) into functional human cell types-unlocking new possibilities for research and cell therapy. Through its proprietary High-Dimensional Design of Experiments (HD-DoE®) platform, Trailhead optimizes differentiation with exceptional accuracy, enabling scalable solutions for both drug discovery and regenerative medicine. The investment, led by MAK Capital with participation from additional investors, comes at a critical phase of Trailhead's growth, enabling expansion in personnel, manufacturing and strategic partnerships.

Trailhead Biosystems is pioneering the informatics-based approach in regenerative medicine and drug discovery. Founded in 2015 as a spinout from the Cleveland Clinic and Case Western Reserve University, Trailhead emerged from the research of CEO/CSO Dr. Jan Jensen during his tenure as an endowed professor at the Cleveland Clinic. Trailhead creates optimized human cells at scale with its proprietary High-Dimensional Design of Experiments (HD-DoE®) platform. HD-DoE® integrates advanced mathematical modeling with high-throughput robotic manufacturing.