Peptilogics, a clinical-stage biotechnology company developing transformative surgical therapeutics to effectively treat and prevent serious medical device infections, today announced the completion of an oversubscribed $78 million Series B2 financing round. The funding will support the company's Phase 2/3 pivotal trial of zaloganan (PLG0206), an investigational treatment for prosthetic joint infections (PJI).

Presight Capital, Thiel Bio, and Founders Fund led the round, with participation from new investors AMR Action Fund, Narya Capital, and Beyond Ventures. This brings Peptilogics' total equity funding to approximately $120 million, along with substantial grant support from CARB-X.

Peptilogics is developing therapeutics for orthopedic hardware-related infections. The company's lead candidate, zaloganan (PLG0206), is an investigational treatment for prosthetic joint infections currently in clinical development.