Google Ventures and Kleiner Perkins co-led the Series B round. Sequoia Capital, which led OpenEvidence's Series A round earlier in 2025, followed on in this round. The round also included investments from Coatue, Conviction, and Thrive. OpenEvidence has raised more than $300 million since its founding.

OpenEvidence is the fastest-growing clinical decision support platform in the United States, and the most widely used medical search engine among U.S. clinicians. Trusted by hundreds of thousands of verified physicians, nurses, and other healthcare professionals, OpenEvidence is actively used across more than 10,000 hospitals and medical centers nationwide and by over 40% of physicians in the United States who log in daily to make high-stakes clinical decisions at the point of care.

OpenEvidence continues to grow by over 65,000 new verified U.S. clinician registrations each month. Aside from Google itself, there has never been a piece of technology adopted by clinicians as quickly as OpenEvidence. OpenEvidence is transforming how frontline healthcare providers access, evaluate, and apply the world's medical knowledge. More than 100 million Americans this year will be treated by a doctor who used OpenEvidence.