Detect-ION, with support from the Bill & Melinda Gates Foundation, will apply its cutting-edge breath diagnostic technology in low- and middle-income countries (LMICs), further driving its vision to develop and apply mass spectrometry for the masses. This visionary project will leverage Detect-ION's chip-scale mass spectrometry for point-of-care breath diagnostics in LMICs, with an initial focus on detecting malaria and tuberculosis (TB) in human subjects across central Africa.