Antithesis announced a $105 million Series A round led by Jane Street, the global technology-driven quantitative trading firm known for building some of the world's most advanced software systems. The investment underscores Antithesis's emergence as critical infrastructure for enterprises operating complex, distributed systems. Jane Street is both an Antithesis investor and customer.

Additional investors include Amplify Venture Partners, Spark Capital, Tamarack Global, First In Ventures, Teamworthy Ventures, Hyperion Capital, and individuals including Patrick Collison, Dwarkesh Patel, and Sholto Douglas, alongside other new and returning investors. The capital will be used to accelerate Antithesis's product innovation and scale its go-to-market operations across North America, Europe, and Asia.