Adrenergics is developing novel therapeutics to treat dilated cardiomyopathy (DCM) in patients that do not respond to existing therapies. Dilated cardiomyopathy is a disease of the muscle of the heart which usually starts in the left ventricle, the chamber of the heart responsible for pumping activity. Thinning of the left ventricle causes it to not pump blood effectively, resulting in inefficient blood supply throughout the body. While the condition may cause no noticeable symptoms, it can cause irregular heartbeat or blood clots and it may be life threatening. Existing DCM treatments, while beneficial for a number of patients, do not address a significant driver of disease progression that is present in a large proportion of DCM patients. Adrenergics is focusing on this key disease driver to develop medicines that are expected to modulate disease progression leading to improved outcomes in this difficult-to-treat patient population.

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